Appendix Table 2.

GEE Logistic Regression Models for Depression by the Presence of rs3745274, rs28399499, and rs4803419 Minor Alleles

No. of copies minor allele	Unadjusted OR (95% CI)	p	Adjusted ORa(95% CI)	p	Wald p-value for added allele × time interaction term
By the presence of rs3745274 allele
0	REF	—	REF	—	.79
1 or 2	1.28 (0.63–2.63)	.49	1.03 (0.49–2.19)	.93
By the presence of rs28399499 allele
0	REF	—	REF	—	.36
1 or 2	1.42 (0.66–3.09)	.37	1.34 (0.59–3.08)	.48
By the presence of rs4803419 allele
0	REF	—	REF	—	.004
1 or 2	0.43 (0.06–3.22)	.41	0.27 (0.48–1.47)	.129

^aEstimated OR based on main effects model adjusted for the following baseline covariates: age, sex, marital status, education, asset index, year of enrollment, CD4⁺ T lymphocyte count, log₁₀ viral load, probable depression, health status, heavy drinking, and study data source.

OR, odds ratio.