Appendix Table 4.

Modified Poisson Regression Models for Viral Suppression by rs3745274, rs28399499, and rs4803419 Minor Allele Copy Number

No. of copies	Unadjusted RR (95% CI)	p	AdjustedaRR (95% CI)	p
By rs3745274 allele copy number
0	REF	—	REF	—
1	1.01 (0.88–1.15)	.92	1.00 (0.88–1.14)	.96
2	1.03 (0.85–1.25)	.75	1.04 (0.85–1.28)	.69
By rs28399499 allele copy number
0	REF	—	REF	—
1	0.95 (0.79–1.15)		0.95 (0.79–1.14)	.56
2	—b	—	—	—
By rs4803419 allele copy number
0	REF	—	REF	—
1	0.84 (0.62–1.13)	.24	0.85 (0.65–1.11)	.24
2	1.20 (1.12–1.28)	<.001	1.09 (0.95–1.24)	.239

^aAdjusted for the following baseline covariates: age, sex, marital status, education, asset index, year of enrollment, CD4⁺ T lymphocyte count, log₁₀ viral load, probable depression, health status, heavy drinking, and study data source.

^bNo participants with two copies of rs28399499 minor allele.

RR, risk ratio.