Table 1.

Number of optimization runs per tissue and average score.

	Adrenal gland	Kidney	Liver	Heart	Skeletal muscle	Lung	Brown adipose	White adipose	SCN	Cerebellum
Number of runs	100	93	57	57	58	31	62	45	153	58
Runs with score < 10	66	59	52	44	35	21	36	22	46	39
Mean score	3.84	4.48	1.58	3.74	5.17	3.04	4.00	3.24	7.21	3.99
Figure	2, 5, 6, 7, 8	2, 5, 6, 7, 8	2–8	8, S2, S5	8, S2, S5	8, S2, S5	8, S2, S5	8, S2, S5	2–8	S2, S5

Four tissues (adrenal gland, kidney, liver, and SCN) are mainly discussed in the main text and others are described in supplements as indicated in the last row.