Table 3.

Adjusted Change in Proportion of Days Covered (PDC) from Pre-Cancer Diagnosis Period to Post-Cancer Diagnosis Period, by Cancer Site and Race/Ethnicity

		Odds Ratio [95% CI]	p-value
By Cancer Type
All cancers (n=10,177)
Pre-cancer		1.0 (Referent)	<.0001
Post-cancer		0.91 [0.88, 0.94]
Breast cancer (n=3,153)
Pre-cancer		1.0 (Referent)	0.011
Post-cancer		0.94 [0.90, 0.99]
Colorectal cancer (n=1,762)
Pre-cancer		1.0 (Referent)	<.0001
Post-cancer		0.79 [0.74, 0.85]
Prostate cancer (n=5,262)
Pre-cancer		1.0 (Referent)	0.657
Post-cancer		1.01 [0.97, 1.05]
By Race/Ethnicity
White, NH (n=6,497)
Pre-cancer		1.0 (Referent)	<0.001
Post-cancer		0.85 [0.85, 0.92]
Asian/Pacific Islander, NH (n=1,074)
Pre-cancer		1.0 (Referent)	0.176
Post-cancer		0.94 [0.86, 1.03]
African American, NH (n=937)
Pre-cancer		1.0 (Referent)	0.368
Post-cancer		0.96 [0.89, 1.05]
Hispanic (n=1,054)
Pre-cancer		1.0 (Referent)	0.596
Post-cancer		0.98 [0.90, 1.06]
Multi-race (n=577)
Pre-cancer		1.0 (Referent)	0.015
Post-cancer		0.86 [0.76, 0.97]
Native American/Alaskan Native (n=33)
Pre-cancer		1.0 (Referent)	0.998
Post-cancer		1.00 [0.68, 1.46]

Notes: Estimates based on generalized estimating equations (GEE) using PROC GENMOD for binomial proportion with logit link function. Overall adherence is defined as proportion of days covered using a multivariable generalized linear model adjusted for cancer site, race-ethnicity, age at diagnosis, year of diagnosis, stage at diagnosis, Charlson Comorbidity Index, time (as one-year periods), sex (for colorectal cancer only), and cancer site-time interaction. Pre-cancer (post-cancer) diagnosis period includes the two-year period prior to (after) cancer. Multi-race patients are those that self-reported more than one race category.