Scheme 4. Reactions of N-aryl glycine with isatins. +Reaction conditions: 1h (0.15 mmol), 4 (0.1 mmol), DPZ (1.0 mol%), C1 (20 mol%), degassed THF (2.0 mL), 10 °C, irradiation with a blue LED (3 W, 450 nm), 36 h. The yield amount was isolated by flash column chromatography on silica gel. ee was determined by HPLC analysis on a chiral stationary phase.
