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. 2018 Aug 23;16(43):8056–8063. doi: 10.1039/c8ob01790e

Table 1. Showing the peptide sequences and spacers incorporated into dual-probe scaffold.

Compound Sequence 1 (thrombin substrates) Sequence 2 (MMP substrates) X2
1 –NleWPRGWRL –GPKGLKG– –K(PEG2)-PEG2
2 –NleWPRGWRL– –PFGNleKβA– –K(PEG2)-PEG2
3 a –NleWPRGWR(d)L– –PFGNleKβA– –K-PEG2
4 a –NleWP(d)RGWR(d)L– –PFGNleKβA– –K-PEG2
5 a –NleWPRGWR(d)L– –PFG(d)NleKβA– –K-PEG2

a d-Aminoacids d-Leu, d-Arg and d-Nle were used where indicated. X1: –PEG2-K(–CO(CH2)2–C Created by potrace 1.16, written by Peter Selinger 2001-2019 CH). Tail: -[PEG2-(d)Lys]3-NH2; Nle:Norleucine.