Skip to main content
. 2018 Nov 2;3(21):e124152. doi: 10.1172/jci.insight.124152

Figure 4. Distinct immune signatures of symptomatic ZIKV infection in different trimesters of pregnancy.

Figure 4

Multiplex immune profiling of 30 inflammatory cytokines and 39 chemokines using serum specimens derived from 30 RJ healthy pregnant women (n = 10/trimester) and 30 symptomatic ZIKV+ women (n = 10/trimester). (A) Venn diagram representation of distinct immune signatures of acute ZIKV infection in each trimester. Red, induced cytokines; blue, repressed cytokines. (B) Heatmap of 10 inflammatory cytokines/chemokines. Fold changes in cytokines are relative to Rio de Janeiro (RJ) healthy and presented as heatmap. Red, white, and blue indicate induction, no change, and repression, respectively.