(A) Quantitative assessment by LC-MS of total CL, CLox, and mCL content in the contusional cortex at 1, 4, and 24 hours after controlled cortical impact (CCI). n = 4/group, *P < 0.05 vs. control, 1-way ANOVA. The box plots depict the minimum and maximum values (whiskers), the upper and lower quartiles, and the median. The length of the box represents the interquartile range. (B) Color contour map showing changes in CL species at 1, 4, and 24 hours with respect to control. Values are average from 4 animals.