Figure 3. Evaluation of CL remodeling pathway proteins following TBI.

(A) Expression levels (relative to mitochondrial marker Tim23) of the CL-remodeling protein iPLA₂γ after CCI in the contusional cortex. n = 5/group, *P < 0.05 vs. control, 1-way ANOVA. The box plots depict the minimum and maximum values (whiskers), the upper and lower quartiles, and the median. The length of the box represents the interquartile range. (B) Expression levels (relative to mitochondrial marker Tim23) of the CL-remodeling protein Taz after CCI in the contusional cortex. n = 5/group, *P < 0.05 vs. control, 1-way ANOVA. (C) Temporal profile of changes in the CL-remodeling protein iPLA₂γ (relative to mitochondrial marker Tim23) after mechanical stretch in HT22 cells. n = 4/group, *P < 0.05 vs. control, 1-way ANOVA. (D) Temporal profile of changes in the CL-remodeling protein Taz (relative to mitochondrial marker Tim23) after mechanical stretch in HT22 cells. n = 4/group, *P < 0.05 vs. control, 1-way ANOVA. (E) Changes in Taz expression (relative to GAPDH) in human contusional brain tissue for TBI patients who underwent resection of contusion within 6 hours or 48 to 72 hours after TBI. n = 5/group, *P < 0.05 vs. control, 1-way ANOVA.