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Studies with 8-BrG substitution of Gs to elucidate folding pattern of RAD17 promoter PQS. Red represents a G in the syn position, blue represents a G in the anti position. (A) T18 Sequence used for studies with positions of the Gs marked. (B) Tm data obtained of sequences with 8-BrG substituted in different positions. (C) Depiction of the fold that the parent sequence adopts.
