Table 1.

Function of CLIC1 in different cancers

Cancer	Sample	Function	Pathway	Reference(s)
Gastric cancer	Tissue	Promotes invasion and migration and inhibits apoptosis	MAPK–Akt	14
Gallbladder cancer	Tissue	Increases drug sensitivity	–	17, 12
Glioblastoma	Tissue	Regulator of glioblastoma growth	–	18
Pancreatic cancer	Tissue	Putative oncogene	–	9
Sarcoma	Tissue	Receptor oncotargets	ERK	23
Colon cancer	Cells	Metastasis	–	11
Breast cancer	Cells	Migrates or invades	–	15
Ovarian cancer	Serum	Serological tumorigenesis biomarkers	–	13, 19, 22
Colorectal cancer	Cells	Migration and invasion	RVD	24
Endometrioid endometrial cancer	Tissue	Chemoresistance	–	21
Laryngeal cancer	Cells	Promotion of ROS production	ROS	10
Nasopharyngeal carcinoma	Tissue/plasma	Plasma tumor marker	–	8
Gallbladder cancer	Cells	Metastasis	–	20
Hepatocellular carcinoma	Cells	New targets for drug development	–	16

Abbreviations: RVD, regulatory volume decrease; ROS, reactive oxygen species.