Table 1.

Clinical characteristics of NETs at different primary sites based on the SEER database

Variables	Total (%)	Colon (%)	Lung/bronchus (%)	Small intestine (%)	Pancreas (%)	Stomach (%)	Rectum (%)
Sex
Male	34,876	4,616	9,200	8,644	4,415	2028	5,973
	(47.3)	(46.6)	(40.8)	(52.7)	(55.6)	(40.4)	(50.0)
Female	38,906	5,284	13,369	7,744	3,531	2,994	5,984
	(52.7)	(53.4)	(59.2)	(47.3)	(44.4)	(59.6)	(50.0)
Year
1973–1986	3,599	687	1,088	1,058	425	106	235
	(4.9)	(6.9)	(4.8)	(6.5)	(5.3)	(2.1)	(2.0)
1987–2000	13,558	1,823	4,791	3,078	1,098	779	1992
	(18.4)	(18.4)	(21.2)	(18.8)	(13.8)	(15.5)	(16.7)
2001–2014	56,625	7,390	16,690	12,252	6,423	4,137	9,730
	(76.7)	(74.6)	(74.0)	(74.8)	(80.8)	(82.4)	(81.4)
Age, years
<50	13,558	2,474	3,373	2,178	1,776	929	2,831
	(18.4)	(25.0)	(14.9)	(13.3)	(22.4)	(18.5)	(23.7)
50–65	27,409	3,677	7,154	5,838	2,939	1,677	6,122
	(37.1)	(37.1)	(31.7)	(35.6)	(37.0)	(33.4)	(51.2)
>65	32,815	3,749	12,042	8,372	3,231	2,416	3,004
	(44.5)	(37.9)	(53.4)	(51.1)	(40.7)	(48.1)	(25.1)
Race
White	58,984	8,039	19,928	13,408	6,437	4,018	7,154
	(79.9)	(81.2)	(88.3)	(81.8)	(81.0)	(80.0)	(59.8)
Black	10,296	1,368	1,853	2,540	902	705	2,928
	(14.0)	(13.8)	(8.2)	(15.5)	(11.4)	(14.0)	(24.5)
Other	4,502	493	788	440	607	299	1,875
	(6.1)	(5.0)	(3.5)	(2.7)	(7.6)	(6.0)	(15.7)
Marital status
Married	45,434	5,903	13,036	10,363	5,252	2,997	7,886
	(61.6)	(59.6)	(57.8)	(63.2)	(66.1)	(59.7)	(66.0)
Unmarried	28,348	399	9,533	6,025	2,694	2025	4,071
	(38.4)	(40.4)	(42.2)	(36.8)	(33.9)	(40.3)	(34.0)
Grade
Good	15,683	1,762	3,211	4,717	2,379	1,244	2,373
	(21.3)	(17.8)	(14.2)	(28.8)	(29.9)	(24.8)	(19.8)
Moderate	4,855	738	1,348	1,169	819	286	493
	(6.6)	(7.5)	(6.0)	(7.1)	(10.3)	(5.7)	(4.1)
Poor	5,531	1,170	2,990	209	523	369	272
	(7.5)	(11.8)	(13.2)	(1.3)	(6.6)	(7.3)	(2.3)
Undifferentiated	2,108	354	1,294	69	182	98	107
	(2.9)	(3.6)	(5.7)	(0.4)	(2.3)	(2.0)	(0.9)
Unknown	45,605	5,876	13,726	10,224	4,043	3,025	8,712
	(61.8)	(59.4)	(60.8)	(62.4)	(50.9)	(60.2)	(72.9)
Stage
Localized	29,367	3,420	7,373	4,697	1,987	2,970	8,911
	(39.8)	(34.5)	(32.7)	(28.7)	(25.0)	(59.1)	(74.5)
Regional	12,659	2,367	3,354	4,987	1,389	335	231
	(17.2)	(23.9)	(14.9)	(30.4)	(17.5)	(6.7)	(1.9)
Distant	16,234	1,891	7,305	2,959	3,206	474	401
	(22.0)	(19.1)	(32.4)	(18.1)	(40.3)	(9.4)	(3.4)
Unknown	15,522	2,222	4,537	3,745	1,364	1,243	2,414
	(21.0)	(22.4)	(20.1)	(22.9)	(17.2)	(24.8)	(20.2)
Surgery
Yes	42,229	7,001	9,156	11,298	3,351	2,660	8,754
	(57.2)	(70.7)	(40.6)	(68.9)	(42.2)	(53.0)	(73.2)
No	19,382	1,030	9,452	1,963	3,437	1,762	1,744
	(26.3)	(10.4)	(41.9)	(12.0)	(43.3)	(35.1)	(14.6)
Unknown	12,171	1,869	3,961	3,127	1,158	600	1,459
	(16.5)	(18.9)	(17.6)	(19.1)	(14.6)	(11.9)	(12.2)
Radiation
Yes	5,517	138	4,314	176	501	125	263
	(7.5)	(1.4)	(19.1)	(1.1)	(6.3)	(2.5)	(2.2)
No	68,265	9,762	18,255	16,212	7,445	4,897	11,694
	(92.5)	(98.6)	(80.9)	(98.9)	(93.7)	(97.5)	(97.8)
Chemotherapy
Yes	11,078	1,376	5,798	925	2,178	390	415
	(15.0)	(13.9)	(25.7)	(5.6)	(27.4)	(7.8)	(3.5)
No	62,704	8,524	16,771	15,463	5,768	4,632	11,542
	(85.0)	(86.1)	(74.3)	(94.4)	(72.6)	(92.2)	(96.5)

Abbreviations: NETs, neuroendocrine tumors; SEER, Surveillance, Epidemiology and End Results.