Table 2.
Salvage reirradiaton and CBS
| Study | No. of patients | RT technique | No. of CBS | Mortality | Survival >1 months |
|---|---|---|---|---|---|
| Dawson et al31 | 40 | 3D-CRT | 1 (2.5%) | 0 | 1 |
| Kasperts et al32 | 39 | 3D-CRT | 0 | ||
| Tanvetyanon et al33 | 103 | Various ± Ch | 1 (1%) | 1 | 0 |
| Rate et al34 | 47 | IORT | 1 (2.1%) | 1 | 0 |
| Stevens et al35 | 100 | EBRT ± brachy | 4 (4%) | 4 | 0 |
| Duprez et al36 | 84 | IMRT | 2 (2.4%) | 2 | 0 |
| Lee et al37 | 105 | IMRT ± Ch | 0 | ||
| Sulman et al38 | 74 | IMRT ± Ch | 0 | ||
| Watkins et al39 | 39 | Ch/Rt | 2 (5.1%) | 1 | 1 |
| De Crevoisier et al40 | 169 | Ch/Rt | 5 (2.9%) | 5 | 0 |
| Salama et al41 | 115 | Ch/Rt | 6 (5.2%) | 5 | 1 |
| Janot et al42 | 60 | Ch/Rt | 1 (1.7%) | 1 | 0 |
| Kramer et al43 | 38 | Ch/Rt | 1 (2.7%) | 1 | 0 |
| Langer et al44 | 83 | Ch/Rt | 2 (2.4%) | 2 | 0 |
| Spencer et al45 | 79 | Ch/Rt | 2 (2.5%) | 2 | 0 |
| Hehr et al46 | 27 | Ch/Rt | 2 (7%) | 2 | 0 |
| Iseli et al47 | 87 | Ch/Rt | 5 (5.7%) | 1 | 3 |
| Lartigau et al48 | 56 | SBRT | 1 (1.8%) | 1 | 0 |
| Cengiz et al49 | 46 | SBRT | 8 (17%) | 7 | 1 |
| Yamazaki et al50 | 381 | SBRT | 32 (8%) | 22 | 10 |
| Yazici et al51 | 75 | SBRT | 11 (14.7%) | 8 | 3 |
| Vargo et al52 | 48 | SBRT | 0 |
Abbreviations: 3D-CRT, three-dimensional conformal radiotherapy; CBS, Carotid blowout syndrome; Ch/Rt, chemoradiotherapy; EBRT, external beam radiotherapy; IMRT, intensity-modulated radiotherapy; IORT, intraoperative radiotherapy; SBRT, stereotactic body radiotherapy.