Fig. 1.

National and International Data Sharing Mechanisms. Data from national genome sequencing initiatives and related clinical data will naturally need to be stored within centralized national storage systems. Anonymized data from the analyses of these projects can be made available for research use, either via controlled-access data repositories or open, public data repositories, depending on consent and data category. Products and Standards developed by GA4GH can be applied by the three different resource types to ensure interoperability of medical genomics data.