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. 2018 Nov 9;38(6):BSR20180854. doi: 10.1042/BSR20180854

Figure 1. Effect of ASA on drug resistance of HCC SP cells.

Figure 1

Flow cytometry analysis and fluorescence-activated cell sorting were performed to isolate non-SP and SP cells from the HCC cell line MHCC-97L. (A) The colony-formation ability of non-SP and SP cells was determined in the absence or presence of Doxo (500 ng/ml); **P<0.01, compared with Non-SP cells. (B) The cell viability of SP cells treated with different concentrations of ASA (0, 1.25, 2.5, and 5 μmol/ml) for 48 h in the presence of Doxo (500 ng/ml) was analyzed by MTT assay; *P<0.05, **P<0.01, compared with control.