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| Subgroups | Number of studies | Number of patients | Pooled HR with 95% CI | P-value | Heterogeneity | |
|---|---|---|---|---|---|---|
| I2 (%) | P-value | |||||
| Sample size | ||||||
| ≤1000 | 3 | 1276 | 2.048 (1.512–2.773) | 0.000 | 0.0 | 0.917 |
| >1000 | 2 | 4257 | 1.369 (1.155–1.623) | 0.000 | 0.0 | 0.900 |
| Cut-off value for CRP/Alb | ||||||
| ≤0.1 | 3 | 4666 | 1.423 (1.210–1.674) | 0.000 | 8.5 | 0.335 |
| >0.1 | 2 | 867 | 2.027 (1.404–2.926) | 0.000 | 0.0 | 0.686 |
