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. 2018 Nov 16;13(11):e0207474. doi: 10.1371/journal.pone.0207474

Table 3. Results of the selected metabolites in breast cancer patients post-radiotherapy (RT), and segregated with respect to whether or not they received adjuvant hormone therapy.

Results are shown as means and SD (in parenthesis).

Variable Metabolite concentrations post-RT
Hormone therapy NO Hormone therapy YES
Pyruvate (μM) 84.26 (32.25) 72.42 (27.48)
Lactate (μM) 578.60 (111.08) 541.46 (112.91)
Alanine (μM) 231.06 (92.05) 206.97 (80.33)
Hydroxybutyrate (μM) 20.11 (15.72) 25.91 (23.10)
Valine (μM) 141.59 (75.31) 121.49 (72.50)
Leucine (μM) 68.97 (41.21) 58.07 (37.34)
Isoleucine (μM) 29.93 (21.50) 24.08 (18.33)
Proline (μM) 90.23 (59.08) 76.01 (51.43)
Malonyl Coenzyme A (μM) 1.50 (0.39) 1.36 (0.43)
Glycine (μM) 122.82 (38.32) 103.04 (40.01) *
Succinate (μM) 11.62 (3.01) 11.04 (2.79)
Fumarate (μM) 0.62 (0.33) 0.48 (0.24)
Serine (μM) 39.31 (31.19) 35.03 (30.44)
Oxaloacetate (μM) 36.41 (14.08) 35.70 (11.20)
Malate (μM) 2.59 (1.46) 2.02 (0.97)
Aspartate (μM) 16.10 (7.14) 15.98 (6.30)
Ketoglutarate (μM) 4.78 (2.72) 4.17 (1.84)
Glutamate (μM) 44.84 (24.13) 52.98 (22.38)
Aconitate (μM) 0.50 (0.34) 0.56 (0.31)
Citrate (μM) 57.44 (14.41) 53.38 (12.90)
Glutamine (μM) 75.01 (23.31) 66.83 (22.30)

* P < 0.05