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Southeast region of Brazil formed by the states of São Paulo (SP), Minas Gerais (MG), Rio de Janeiro (RJ) and Espírito Santo (ES). The red points represent the hometowns of the families (Botucatu, Tanabi and Mogi das Cruzes). Yellow points represent the hometowns of the unrelated patients (Campinas, Limeira, Americana, Mogi Guaçu, Jundiaí, Pirassununga, Itapira and Paraguaçu Paulista).
