Table 4:

Time series analysis for HO-CDI rates

Factor	BMT service vs control
	Coefficient	p-value
Intercept in control unit (HO-CDI per 10,000 patient days)	7.29	0.004
Slope in control unit pre-intervention (change in HO-CDI per 10,000 patient days per month)	−0.04	0.82
Immediate effect in control unit at time of intervention (HO-CDI per 10,000 patient days)	−0.82	0.84
Difference between pre- and post-intervention slopes in control unit (change in HO-CDI per 10,000 patient days per month)	−0.11	0.78
Difference in intercept of transplant vs. control unit (HO-CDI per 10,000 patient days)	69.45	<0.001
Difference in pre-intervention slope between transplant vs control units (change in HO-CDI per 10,000 patient days per month)	−1.42	0.048
Difference in immediate effect at time of intervention between transplant vs. control units (HO-CDI per 10,000 patient days)	−11.83	0.37
Difference between pre-and post-intervention slopes in the transplant vs. control unit, i.e. difference in differences of the slopes (change in HO-CDI per 10,000 patient days per month)	−0.11	0.93

BMT: Bone marrow transplant; HO-CDI: Hospital onset Clostridium difficile infection;