Table 7.

Ideal deal drug delivery platforms based on patterns of locoregional recurrence

Cancer	Ideal Novel Drug Delivery Platform
Rectal Cancer	•Nanoparticle (intravenous or intraperitoneal) •Hydrogel at anastomosis •Polymer film along pelvic side wall
Breast Cancer	•Nanoparticle (intravenous or peritumoral) •Polymer film in resection bed
Mesothelioma	•Intrapleural nanoparticle •Polymer film (after pneumonectomy/decortication)
Non-Small Cell Lung Cancer	•Polymer film along staple line •Systemic nanoparticle/dendrimer/liposome
Retroperitoneal Sarcoma	•Polymer film in resection bed
Peritoneal Surface Malignancies	•Intraperitoneal nanoparticle