Figure 1b.

Transition probabilities in the COPDGene Cohort - included in the longitudinal analysis were the ‘Cough only’ and ‘Fixed airflow obstruction only’ states which were not included in the cross-sectional analysis.(n=2761)

Multi-state Markov-like model analyzing longitudinal transition probabilities between productive cough disease severity states over approximately 5 years in the COPDGene cohort. The table is read vertically with the header representing the baseline state and each column in the vertical axis the transition probabilities to all possible states. Strength of transition probabilities is reflected by the percentage in each cell. Light grey cells denote the PC stage and white cells the non-PC stages. Dark grey cells following the diagonal axis of the table represent transition probabilities of staying within the same severity stage between study examination visits at 5-year intervals.