Table 1. Patients and tumor characteristics.
| Characteristic | Age > 80 years (group A) 13 Pts. (%) | Age < 80 years (group B) 356 Pts. (%) | Age < 80 years (group A vs B) p -Value | Matched a (group C) age < 80 years 13 Pts (%) | Matched a age <80 years (group A vs C) p -Value |
|---|---|---|---|---|---|
| Age (years, (IQR)) | 83.4 (80.6, 84.5) | 51.8 (42,76.3) | <0.01 | 66.5 (60.5, 72.9) | < 0.01 |
| Male | 7 (53.8) | 202 (55) | 0.932 | 7 (53.8) | > 0.999 |
| Major comorbidities | 12 (92.3) | 147 (41.9) | <0.01 | 11 (84.6) | > 0.999 |
| Minor comorbidities | 0 (0) | 39 (11.1) | 0.376 | 1 (7.7) | 0.317 |
| Recurrent/persistent disease | 9 (69.2) | 171 (49.6) | 0.164 | 7 (53.8) | 0.625 |
| Malignant pathology | 10 (76.9) | 134 (37.4) | 0.004 | 12 (92.3) | 0.5 |
| Anterior skull base | 3 (23.1) | 236 (66.3) | 0.031 | 1 (7.7) | 0.625 |
| Lateral skull base | 10 (76.9) | 120 (33.7) | 0.031 | 12 (92.3) | 0.625 |
| Lumbar drainage | 1 (8.3) | 138 (43) | 0.017 | 8 (61.5) | > 0.999 |
| Preoperative surgery | 7 (53.8) | 159 (45.2) | 0.537 | 5 (38.5) | > 0.999 |
| Preoperative chemoradiotherapy | 5 (38.5) | 63 (17.9) | 0.074 | 3 (23.1) | > 0.999 |
| Adjuvant chemoradiotherapy | 8 (61.5) | 88 (28) | 0.024 | 1 (7.7) | > 0.999 |
| Hospitalization days (IQR) | 10 (7.5, 15) | 10 (7,13) | 0.554 | 1 (10) | > 0.999 |
Abbreviations: IQR, interquartile range; Pts, patients; Yrs, years.
a
Group C—Thirteen patients matched by gender, major and minor comorbidities, preoperative treatment (surgery/chemoradiotherapy), status of the disease (primary vs recurrence/persistence), surgical intracranial or dural extension, benign or malignant pathology, and site of skull base involvement (lateral/anterior).