Table 3. Surgical extension to skull base compartments and free flap reconstruction.
| Characteristic | Age > 80 years (group A) 13 Pts. (%) | Age < 80 years (group B) 356 Pts. (%) | Age < 80 years (group A vs B) p -Value | Matched a age < 80 years (group C) 13 Pts (%) | Matched a Age < 80 years (group A vs C) p -Value |
|---|---|---|---|---|---|
| Orbital extension | 3 (23.1) | 141 (42.4) | 0.165 | 4 (30.8) | > 0.999 |
| Intracranial extension | 1 (7.7) | 175 (49.2) | 0.003 | 3 (23.1) | 0.5 |
| Pterygopalatine fossa extension | 1 (7.7) | 43 (12.1) | > 0.999 | 2 (15.4) | > 0.999 |
| Dural extension | 4 (30.8) | 220 (61.8) | 0.024 | 4 (30.8) | > 0.999 |
| Infratemporal fossa extension | 5 (41.7) | 65 (20.4) | 0.14 | 7 (53.8) | 0.754 |
| Cavernous sinus extension | 0 (0) | 24 (7.6) | > 0.999 | 1 (7.7) | 0.317 |
| Free flap reconstruction | 3 (25) | 45 (13.9) | 0.39 | 4 (30.8) | > 0.999 |
Abbreviations: Pts, patients; Yrs, years.
a
Group C—Thirteen patients matched by gender, major and minor comorbidities, preoperative treatment (surgery/chemoradiotherapy), status of the disease (primary vs recurrence/persistence), surgical intracranial or dural extension, benign or malignant pathology, and site of skull base involvement (lateral/anterior).