Table 2.

Discrimination for gastric adenocarcinoma (GAC) of the top 16 methylated DNA marker candidates selected following discovery and technical validation.

	GAC vs Normal Mucosa			GAC vs Buffy Coat
	AUC	Fold-Change	p-value	AUC	Fold-Change	p-value
RHGEF4	0.95	153	< 0.0001	0.94	80	< 0.0001
ELMO1	0.95	208	< 0.0001	0.99	3340	< 0.0001
ABCB1	0.97	48	< 0.0001	0.89	14.2	< 0.0001
BMP3	0.92	120	< 0.0001	0.86	5.92	< 0.0001
SP9	0.91	131	< 0.0001	0.94	21381	< 0.0001
CLEC11A	0.95	223	< 0.0001	0.94	83.4	< 0.0001
EMX1	0.95	883	< 0.0001	0.94	13621	< 0.0001
ST8SIA1	0.93	67.9	< 0.0001	0.94	185	< 0.0001
CD1D	0.91	237	< 0.0001	0.87	135	< 0.0001
SFMBT2	0.99	711	< 0.0001	0.98	1128	< 0.0001
CYP26C1	0.94	597	< 0.0001	0.94	11243	< 0.0001
PKIA	0.94	183	< 0.0001	0.91	40.0	< 0.0001
NDRG4	0.88	288	< 0.0001	0.89	>30000	< 0.0001
ZNF569	0.88	3.71	0.0095	0.99	148	< 0.0001
PPP2R5C	0.89	147	< 0.0001	0.97	648	< 0.0001
C13ORF18	0.82	7.45	< 0.0001	0.89	41.4	< 0.0001