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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: J Neural Eng. 2018 Aug 21;15(6):066002. doi: 10.1088/1741-2552/aadbb2

Figure 7. A single fiber would primarily interface with neurons in close proximity to the tip, based on the tissue scattering and absorption.

Figure 7.

The normalized log intensity emission profile of an optical microfiber with tip positioned at [0, 0]. The profile is a Monte Carlo simulation of photon packets propagating through brain tissue, with scattering and absorption properties estimated for 490 nm light. The simulated profile shows a strong interaction with tissue immediately below the tip of the fiber, enabling localized photometry or stimulation; the weak interactions with a larger volume of tissue will contribute background in recordings, or delocalized optogenetic excitation.