Table 3.
Mean (SD) volume in mm3 of targeted brain regions before and after temporal lobe resection (TLR). Dark gray boxes show mean values that decreased significantly (p < 0.05) on the lesioned side from the pre-op to the post-op periods, whereas light gray boxes indicate mean values that increased significantly across these two periods on the non-lesioned side. Sample sizes based upon data where equal numbers of pre- and post-non-resected volumes were available. See text for details.
| LEFT RESECTION GROUP | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Brain Structure | PRE-RESECTION | POST-RESECTION | COMPARATIVE STATISTICS | ||||||||
| N | Mean (SD) Volume Resected Side (L) | Mean (SD) Volume Non-Resected Side (R) | Mean (SD) Volume Resected Side (L) | Mean (SD) Volume Non-Resected Side (R) | % Change Resected Side (L) | t | p* | % Change Non-Resected Side (R) | t | p* | |
| Amygdala | 7 | 878.59 (203.46) | 824.80 (163.10) | ----** | 1,190.66 (185.29) | ----** | ---- | ---- | +44.36 | 4.20 | 0.014 |
| Cerebellum | 8 | 60,607.02 (17,905.88) | 60,949.41 (16,461.75) | 64,308.19 (15,523.96) | 63,182.63 (16,202.40) | +6.11 | 1.88 | 0.103 | +3.66 | 1.48 | 0.181 |
| Hemisphere | 8 | 485,208.71 (55,449.27) | 508,923.304 (59,190.20) | 455,839.12 (58,762.31) | 515,559.05 (61,107.11) | −6.05 | 10.64 | <0.0001 | +1.30 | 2.22 | 0.062 |
| Hippocampus | 7 | 1,415.14 (453.60) | 1,728.88 (112.70) | ----** | 1,854.00 (224.30) | ----** | ---- | ---- | +7.24 | 2.61 | 0.040 |
| Parahippocampal Gyrus | 8 | 9,582.51 (1,245.68) | 9,238.90 (800.86) | 6,304.37 (1,440.62) | 9,538.68 (939.76) | −34.21 | 10.77 | <0.0001 | +3.24 | 2.66 | 0.032 |
| Fusiform Gyrus | 8 | 12,973.19 (1,164.14) | 13,425.11 (1,183.91) | 8,045.33 (1,729.12) | 14,016.86 (1,865.92) | −37.98 | 14.49 | <0.0001 | +4.41 | 4.11 | 0.005 |
| Inferior Temporal Gyrus | 8 | 14,770.73 (2,141.89) | 19,066.23 (2,384.56) | 10,506.71 (2,407.59) | 19,858.13 (2,675.96) | −28.87 | 9.93 | <0.0001 | +4.15 | 2.77 | 0.028 |
| Middle Temporal Gyrus | 8 | 20,233.18 (1,999.73) | 20,872.89 (2,505.39) | 16,811.28 (2,621.88) | 21,355.94 (2,774.80) | −16.91 | 7.90 | <0.0001 | +2.31 | 2.09 | 0.075 |
| Superior Temporal Gyrus | 8 | 25,409.71 (1,954.22) | 28,101.40 (2,564.62) | 24,385.51 (2,871.79) | 28,994.99 (2,946.74) | −4.03 | 1.59 | 0.078 | +3.18 | 2.37 | 0.049 |
| RIGHT RESECTION GROUP | |||||||||||
| Brain Structure | PRE-RESECTION | POST-RESECTION | COMPARATIVE STATISTICS | ||||||||
| N | Mean (SD) Volume Resected Side (R) | Mean (SD) Pre-Non-Resected Side (L) | Mean (SD) Volume Resected Side (R) | Mean (SD) Volume Non-Resected Side (L) | % Change Resected Side (R) | t | p | % Change Non-Resected Side (L) | t | P | |
| Amygdala | 12 | 1196.53 (561.74) | 914.97 (309.69) | ----** | 1,162.06 (190.24) | ----** | ---- | ---- | +27.00 | 2.05 | 0.074 |
| Cerebellum | 12 | 62,216.72 (15,261.10) | 62,275.69 (14,968.83) | 60,135.31 (15,266.71) | 61,333.79 (15,079.60) | −3.35 | 0.75 | 0.468 | −1.51 | 0.29 | 0.777 |
| Hemisphere | 12 | 473,438.45 (70,960.82) | 467,450.53 (71,367.87) | 420,935.44 (82,256.35) | 459,685.87 (89,363.90) | −11.09 | 4.87 | <0.0001 | −1.67 | 0.64 | 0.538 |
| Hippocampus | 12 | 1,321.65 (426.35) | 1,670.75 (284.82) | ----** | 1,630.49 (285.19) | ----** | ---- | ---- | −2.41 | 0.75 | 0.460 |
| Parahippocampal Gyrus | 12 | 8,602.79 (800.87) | 9,625.17 (1,245.69) | 6,429.55 (1,044.80) | 9,963.04 (1,479.52) | −25.26 | 6.57 | <0.0001 | +3.50 | 3.77 | 0.003 |
| Fusiform Gyrus | 12 | 12,087.22 (1,331.93) | 12,806.07 (1,183.91) | 7,223.85 (2,024.28) | 12,790.03 (1,400.77) | −40.24 | 9.93 | <0.0001 | −0.13 | 0.07 | 0.946 |
| Inferior Temporal Gyrus | 12 | 17,859.85 (2,257.14) | 15,290.39 (6,906.79) | 11,711.55 (2,579.37) | 14,483.23 (1,961.29) | −34.43 | 7.62 | <0.0001 | −5.28 | 1.20 | 0.255 |
| Middle Temporal Gyrus | 12 | 19,417.31 (2,505.41) | 19,498.08 (2,183.82) | 13,031.89 (2774.84) | 19,868.59 (2,608.24) | −32.53 | 8.46 | <0.0001 | +1.90 | 0.63 | 0.540 |
| Superior Temporal Gyrus | 12 | 24,618.04 (2,564.65) | 25,213.12 (2,837.10) | 20,229.71 (4,012.47) | 25,365.23 (3,476.84) | −17.83 | 5.51 | <0.0001 | +0.60 | 0.25 | 0.809 |
*
Paired t-tests are one-tailed for resection sides and two-tailed for non-resection sides.
**
too few cases in which post- resection structures were present and could be reliably measured and compared.