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. 2018 Nov 16;1:197. doi: 10.1038/s42003-018-0199-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A comparison of equine chromosome 31 between EquCab2 and EquCab3. a Average coverage per 10 kb window across chr31 in EquCab2 and EquCab3, with a large inversion between them highlighted. EquCab3 has fewer coverage drops and more total sequence than EquCab2. b An alignment of chr31 in EquCab2 and EquCab3 shows a large inversion between the two reference genomes. The radiation hybrid (RH) map (c) and Hi-C contact heat maps for EquCab2 (d) and EquCab3 (e) indicate that this discrepancy is the result of a misassembly in EquCab2