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. 2018 Nov 16;8:16958. doi: 10.1038/s41598-018-35287-6

Table 2.

Brain regions that show a significantly higher connectivity with the early visual cortex during the presentation of cue sounds, versus control sounds (not previously paired with object-location information, left panel).

# Region X Y Z Peak Z-value Cluster Size P-value
1 anterior cingulate cortex 16 14 36 3.75 2218 0.003**
dorsomedial prefrontal cortex −10 30 54 3.65
dorsomedial prefrontal cortex −10 36 56 3.5
rostral cingulate cortex −2 −6 42 3.38
dorsomedial prefrontal cortex −6 44 44 3.35
Supplementary motor area 0 2 44 3.35
2 L hippocampus −32 −16 −18 3.36 271 0.006*
3 R hippocampus 26 −18 −18 2.69 13 0.031*
4 L parahippocampal gyrus −26 −22 −26 3.1 180 0.010*
5 L thalamus −6 −16 12 2.81 215 0.013*
6 R thalamus 2 −16 12 2.67 74 0.016*

Listed are the local maxima of the significant cluster, as well as clusters found in pre-defined anatomical regions of interest. The critical p-value was calculated to correct for multiple (six) comparisons done across anatomical regions of interest, using the Benjamin & Hochberg procedure (1995) to control the false discovery rate. The critical p-value thus calculated was p = 0.031.

**Region that was significant using multiple comparison correction for the whole brain using Gaussian Random Field Theory and a threshold of p < 0.05.

*Region that was significant using a multiple comparison correction for a reduced search volume defined by anatomical regions of interest, and a subsequent correction for the false discovery rate (critical p-value = 0.031).