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. 2018 Nov 16;9:4831. doi: 10.1038/s41467-018-07316-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Deletion of Glut1 with Col2-Cre impairs chondrocyte proliferation and maturation. a H&E staining of longitudinal femoral sections from normal (Ctrl) versus Col2-Cre; Glut1^f/f (Col2-CKO) littermate embryos at E18.5. b–d Immunofluorescence staining of Glut1 (b), ColX (c) or Mmp13 (d) on E18.5 femoral sections. e EdU labeling of chondrocytes in the femur at E18.5. Signal is in red. *p < 0.05, n = 3 mice, error bar indicates SD, two-tailed Student’s t-test. Scale bar: 200 µm