Table 2.
Phenotypic antibiotic susceptibilities of serogroup 19 isolates from children <5 years of age, in NSW.
| Serogroup 19 (%)[19A] | |||
|---|---|---|---|
| Year | 2004 | 2008 | 2014 |
| Total serogroup 19 isolates | 41 [9] | 60 [56] | 23 [16] |
| MDR isolates | 3 (7) [0] | 5 (8)a [3] | 4 (17.4)a [3] |
| Penicillin resistant (MIC <2 µg/mL) | 5 (12) [0] | — | 1 (4.3) [1] |
| Penicillin intermediate (MIC 0.12–1 µg/mL) | 8 (20) [5]b | 36 (60) [35]b,c | 1 (4.3)c [1] |
| Penicillin susceptible (MIC <0. 06 µg/mL) | 25 (61) [3] | 19 (32) [17] | 17 (74) [11] |
Notes:
aSmall numbers of MDR isolates, but increase in proportion in 2014, mainly serotype 19A; difference not significant due to small numbers.
bIncrease in penicillin intermediate isolates between 2004 and 2008, p = 0.0001.
cDecrease in penicillin intermediate isolates between 2008 and 2014, p = 0.0001.
MDR – multidrug resistant - resistant to penicillin, ceftriaxone and erythromycin: MIC – minimum inhibitory concentration.