Table 1.

Clinical characteristics of PWS and OB subjects.

Patient ID	Karyotype	Sex	Age (years)	Height (m)	Weight (kg)	BMI (kg/m2)	Waist circ.	Hip circ. (cm)	WHR	Fat massa (%)	Fat free massa (%)	Systolic blood pressure (mmHg)	Diastolic blood pressure (mmHg)	Liver steatosis (degree)	Primary amenorrhea	Sex steroid therapy	Current GH therapy	Previous GH therapy
1PWS	del15	M	42.4	1.51	90.8	39.9	147	123	1.20	38.5	61.5	120	80	No	–	No	Yes	No
2PWS	del15	M	29.1	1.55	69.7	29.1	104	103	1.01	41.8	58.2	120	70	Yes (1)	–	No	No	No
3PWS	del15	M	42.8	1.57	76.4	30.9	103	104	0.99	30.2	69.8	120	80	No	–	No	Yes	No
4PWS	del15	M	24.8	1.44	63.2	30.4	102	102	1.00	44.6	55.4	120	80	Yes (2)	–	No	No	No
5PWS	del15	F	47.2	1.41	91.7	46.1	121	124	0.98	56.6	43.4	130	80	Yes (1)	No	No	No	No
6PWS	del15	F	30.9	1.44	80.6	39.1	106	120	0.88	52.8	47.2	130	80	No	Yes	Yes	No	No
7PWS	del15	F	22.2	1.65	89.2	32.8	112	117	0.96	44.3	55.7	120	80	No	Yes	Yes	Yes	NO
8PWS	del15	F	35.3	1.66	92.0	33.5	106	118	0.90	46.2	53.8	130	80	Yes (1)	Yes	Yes	No	Yes
9PWS	del15	F	45.9	1.43	97.0	47.4	134	130	1.03	56.9	43.1	120	70	Yes (1)	No	No	No	No
10PWS	del15	F	36.75	1.58	108	43.5	105	136	0.77	50.4	49.6	130	80	No	Yes	Yes	No	Yes
Mean			35.7	1.5	85.9	37.3	114.0	117.7	1.0	46.2	53.8	124.0	78.0
St. Dev			8.8	0.1	13.4	6.8	15.3	11.6	0.1	8.3	8.3	5.2	4.2
1OB	–	M	35.1	1.75	144.0	47.0	124	142	0.87	40.1	59.9	130	80	No		–
2OB	–	M	28.6	1.82	149.2	45.0	141	138	1.02	42.0	58.0	160	90	Yes (2)		–
3OB	–	M	37.25	1.77	124.6	39.8	124	133	0.93	37.8	62.2	120	80	Yes (1)		–
4OB	–	M	31.5	1.68	101.3	36.0	105	114	0.92	35.8	64.2	140	70	No		–
5OB	–	F	29.0	1.70	110.2	38.1	114	130	0.88	48.3	51.7	120	80	Yes (1)		Yesb
6OB	–	F	35.9	1.57	128.4	52.1	126	138	0.91	58.3	41.7	120	70	No		Nob
7OB	–	F	38.2	1.64	122.6	45.6	127	132	0.96	56.3	43.7	110	80	Yes (1)		Yesb
8OB	–	F	44.0	1.65	88.1	32.5	109	113	0.96	42.5	57.5	110	80	No		Nob
9OB	–	F	39.7	1.64	124.4	46.3	123	137	0.90	42.9	57.1	120	70	No		Nob
10OB	–	F	24.0	1.60	103.2	40.3	104	125	0.83	48.9	51.1	120	80	Yes (1)		Yesb
Mean			34.3	1.7	119.6	42.3	119.7	130.2	0.9	45.3	54.7	125.0	78.0
St. Dev			6.0	0.1	19.1	5.9	11.6	10.0	0.1	7.5	7.5	15.1	6.3

^aDetermined by bioelectrical impedance analysis (Human-IM Scan; DS-Medigroup, Milan, Italy). ^bSex steroid therapy for contraceptive purpose.