Table 3.
Univariate Cox analysis of factors in relation to all-cause mortality and cardiovascular events
| Unite increase | All-cause mortality (n = 77) | Fatal and non-fatal cardiovascular events (n = 57) | |||
|---|---|---|---|---|---|
| HR (95%) | p value | HR (95%) | p value | ||
| Age | 1 year | 1.06 (1.04–1.08) | < 0.001 | 1.04 (1.02–1.07) | < 0.001 |
| Male gender | – | 0.94 (0.60–1.46) | 0.8 | 0.88 (0.53–1.48) | 0.6 |
| Diabetes mellitus | – | 2.39 (1.52–3.77) | < 0.001 | 2.29 (1.35–3.89) | 0.002 |
| Hypertension | – | 4.75 (0.66–34.18) | 0.1 | 3.52 (0.49–25.46) | 0.2 |
| Background AVD | – | 4.94 (3.10–7.88) | < 0.001 | 4.59 (2.69–7.85) | < 0.001 |
| Background VC | – | 2.02 (1.25–3.26) | 0.004 | 1.33 (0.73–2.41) | 0.3 |
| Ca × P | 1 mg2/dL2 | 1.0 (0.98–1.01) | 0.4 | 1.0 (0.98–1.01) | 0.6 |
| iPTH | 1 pmol/L | 1.0 (0.99–1.0) | 0.4 | 0.99 (0.99–1) | 0.2 |
| hs-CRP | 1 mg/L | 1.02 (1.0–1.03) | 0.03 | 1.01 (0.99–1.03) | 0.2 |
| Serum albumin | 1 g/L | 0.91 (0.86–0.95) | < 0.001 | 0.91 (0.89–0.97) | 0.001 |
| Hemoglobin | 1 g/L | 1.0 (0.98–1.01) | 0.7 | 1.00 (0.99–1.02) | 0.8 |
| LDL cholesterol | 1 mmol/L | 1.19 (0.99–1.44) | 0.06 | 1.31 (1.09–1.57) | 0.004 |
| LV mass index | 1 g/m2 | 1.002 (0.99–1.01) | 0.2 | 1.004 (1.0–1.008) | 0.05 |
| Log10 Angpt-2 | 1 ng/mL | 3.67 (1.43–9.45) | 0.007 | 6.71 (2.15–20.88) | 0.001 |
| Residual renal function | 1 mL/min | 0.93 (0.83–1.04) | 0.2 | 0.97 (0.86–1.10) | 0.7 |
Calcium × phosphorus product in mg2/dL2 to mmol2/L2, × 0.0806
AVD atherosclerotic vascular disease, VC valvular calcification, Ca × P calcium × phosphorus product, iPTH intact parathyroid hormone, hs-CRP high sensitive C-reactive protein, LDL lower-density lipoprotein, LV left ventricular, Angpt-2 angiopoietin-2