Table 5.
Multivariate Cox regression models for ftal and non-fatal cardiovascular events [expressed as hazard ratios (95% confidence intervals), p-value]
| Unit increase | HR (95%) | p value | |
|---|---|---|---|
| Age | 1 year | 1.03 (0.99–1.06) | 0.07 |
| Male gender | – | 0.52 (0.25–1.08) | 0.08 |
| Diabetes mellitus | – | 1.11 (0.59–2.09) | 0.7 |
| LDL cholesterol | 1 mmol/L | 1.06 (0.78–1.45) | 0.7 |
| LV mass index | 1 g/m2 | 1.01 (1.00–1.01) | 0.04 |
| Log10 Angpt-2 | 1 ng/mL | 4.53 (1.24–16.47) | 0.02 |
| hs- CRP | 1 mg/L | 1.00 (0.97–1.03) | 0.9 |
| Serum albumin | 1 g/L | 0.97 (0.90–1.05) | 0.4 |
| Background VC | – | 0.52 (0.24–1.13) | 0.1 |
| Background AVD | – | 3.11 (1.60–6.05) | 0.001 |
AVD atherosclerotic vascular disease, VC valvular calcification, hs-CRP high sensitive C-reactive protein, LDL lower-density lipoprotein, LV left ventricular, Angpt-2 angiopoietin-2