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. 2018 Nov 16;18:1128. doi: 10.1186/s12885-018-5027-9

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Kaplan–Meier curves showing the association of aberrant expression of BKCa, ERK1/2 and p-ERK1/2 with disease-free survival (DFS) and overall survival (OS) in 185 patients with type I endometrial cancer. High expression of p-ERK1/2 (c, f) was significantly associated with shorter DFS (p = 2.81E^− 4) and OS (p = 4.18E^− 4) in endometrial adenocarcinoma patients; in contrast, both BKCa and ERK1/2 expressions were not significantly associated with DFS or OS (a-e)