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. 2018 Nov 17;17:159. doi: 10.1186/s12943-018-0907-9

Fig. 1.

Fig. 1

Tob1 is upregulated in colon cancer. a Tob1 expression in Kaiser’s colon cancer dataset from Oncomine. b-c Tob1 levels in colon cancer by WB. “N”-normal, “T”-tumour. Tob1 levels were normalized to β-actin levels. “T” vs “N”, n = 5, P = 0.008, Mann-Whitney U test. d-e Tob1 expression was analysed by IHC based on a TMA containing 84 colon cancer specimens. f ROC curve for Tob1. g-h Kaplan-Meier OS curves for patients with different Tob1 expression levels