Fig. 1.

Proteins involved in chromatin organization and NE homeostasis across eukaryotes. The presence/absence and the degree of conservation of homologs identified for chromatin organization and NE homeostasis proteins are shown. Red filled squares represent the homologs validated using rBLAST with significant E-value (less than 10^− 5). The green-filled squares represent the homologs that can be found only using hmmsearch and share conserved region/domain. The supergroups Opisthokonta, Ameobozoa, Excavata, SAR and Archaeplastida are shaded in purple, blue, brown, pink and green filled rectangles, respectively