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. 2018 Nov 16;15:23. doi: 10.1186/s12950-018-0198-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — The inflammasome mediates oxidative stress resulting in LDH release and production of ROS: Bar graph of LDH released by human fibroblasts (49 y/o) after exposure to hydrogen peroxide (25 μM H2O2) for 30 min (a) and in 52 y/o cells after inhibition of caspase-1 with YVAD (b). Cellular ROS production after challenge of 52 y/o fibroblasts with 25 μM H2O2 for 30 min and inhibition of caspase-1 with YVAD (c)