Table 4.

Adjusted^* and unadjusted odds ratios for receipt of radiation therapy and chemoradiation therapy by age group in subgroups in which adjuvant therapy is warranted

	Subgroup with pT3 or pT4 disease or pN2 or pN3 disease (n= 11,361)		Subgroup with ECE present or margin-positive disease (n = 4185)
	OR for receipt of radiation therapy (95% CI)	P value	OR for receipt of chemoradiation therapy (95% CI)	P value
Unadjusted
Age <70 y	Reference	-	Reference	-
Age 70–79 y	0.65 (0.59–0.71)	<.0001	0.46 (0.38–0.54)	<.0001
Age ≥80 y	0.38 (0.33–0.42)	<.0001	0.17 (0.13–0.24)	<.0001
Adjusted*
Age < 70 y	Reference	-	Reference	-
Age 70–79 y	0.67 (0.61–0.75)	<.0001	0.50 (0.41–0.61)	<.0001
Age ≥80 y	0.40 (0.35–0.45)	<.0001	0.19 (0.14–0.27)	<.0001

Abbreviations: CI = confidence interval; ECE = extracapsular extension; OR = odds ratio.

^*Adjusted for sex; race; year of diagnosis; comorbidity score; region of country; facility; oral cavity site; distance from facility; income; and urban, metropolitan, or rural residence.