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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: J Steroid Biochem Mol Biol. 2018 Jun 22;184:11–19. doi: 10.1016/j.jsbmb.2018.06.014

Figure 2. A new NR3E family at the base of the bilaterian ER/ERR/SR clade.

Figure 2.

The tree was calculated using maximum-likelihood. Likelihood ratio test branch support values upper than 0.70 are indicated. Bilaterian sequences are shown in blue and cnidarian sequences in brown. The Hydra NR3E is highlighted in red. Mollusc and annelid NR3Ds correspond to proteins that were previously labelled as ERs [46], Similar analyses using the LBD alone gave largely similar results and did not affect the placement of the cnidarian nuclear receptors.