Figure 5 -.

Summary of neurogenesis in the developing (A) mouse and (B) human cerebellum. Human cerebellar development is highly protracted compared to mice. In mice, the cerebellum develops over a period of 30–35 days with peak EGL expansion, foliation and IGL formation and Purkinje cell maturation occurring during the first two postnatal weeks. In striking contrast, human cerebellar development extends from the early first trimester to final circuit maturity which is achieved by the end of the second postnatal year. Also, a significant portion of human cerebellar development occurs in utero, including peak proliferation of GNPs and folia formation during the last trimester. Reference: Haldipur P., Dang D., and Millen K.J., (In press) Embryology. In: M. Manto and T.A.G.M. Huisman (Eds.) The cerebellum in children and adults. Elsevier, Amsterdam