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. Author manuscript; available in PMC: 2018 Nov 18.
Published in final edited form as: Nat Rev Gastroenterol Hepatol. 2017 Sep 27;14(12):711–726. doi: 10.1038/nrgastro.2017.126
Grade Criteria
0 No stage 1–4 of any organ involvement
I Stage 1–2 skin involvement, without liver, upper gastrointestinal or lower gastrointestinal involvement
II Stage 3 skin involvement and/or stage 1 liver involvement and/or stage 1 upper gastrointestinal involvement and/or stage 1 lower gastrointestinal involvement
III Stage 2–3 liver involvement and/or stage 2–3 lower gastrointestinal involvement with stage 0–3 skin involvement and/or stage 0–1 upper gastrointestinal involvement
IV Stage 4 skin, liver or lower gastrointestinal involvement, with stage 0–1 upper gastrointestinal involvement

BSA, body surface area. Tables from REF. 107, Macmillan Publishers Limited.