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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Am J Clin Oncol. 2019 Jan;42(1):12–16. doi: 10.1097/COC.0000000000000468

Table 1. Outpatient docetaxel-based IP chemotherapy protocol.

Day 0

  • Dexamethasone 8mg p.o.

Day 1

  • Intravenous pre-hydration of 1Liter (L) 0.9% Saline

  • Pre-chemotherapy IV medications: dexamethasone 10mg, diphenhydramine 50mg, fosaprepitant 150mg, palonosetron 0.25mg, and ranitidine 50mg

  • Intravenous Docetaxel 75mg/m2, administered over 1hour (h)

  • Intraperitoneal Cisplatin 75mg/m2, to gravity in 1L 0.9% Saline flushed with 500mL 0.9% Saline and administered over 1h

Day 2-5

  • Dexamethasone 8mg p.o.

Day 8

  • Pre-chemotherapy IV medications: dexamethasone, diphenhydramine, fosaprepitant, palonosetron, and ranitidine

  • Intraperitoneal Paclitaxel 60mg/m2, to gravity in 1L 0.9% Saline flushed with 500mL 0.9% Saline and administered over 1h

  • Pegfilgrastim 6mg subcutaneously