Table 1.

Characteristics of pregnant FMR1 premutation carriers undergoing CVS or AC due to high risk^# for an affected child

Characteristics	Chose IVF-PGT-M 26 women (in 37 pregnancies)	Chose to conceive spontaneously 52 women (in 138 pregnancies)	p value
Maternal age at pregnancy [mean (SD) years]	32.9 (±3.9)	31.4 (±3.7)	0.03
Maternal BMI [kg/m2 (SD)]	21.3 (±3.4)	21.7 (±3.9)	ns
Other genetic disease [%]	21.6	15.9	ns
Infertility [%]	8.1	5.1	ns
Nullipara [%]	17.1	22.1	ns

^#Having 70 or more CGG repeats or having a previous pregnancy affected with FXS

CVS chorionic villus sampling, AC amniocentesis