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. 2018 Nov 19;9(11):208. doi: 10.1038/s41424-018-0076-6

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Percentages of immunoreactive cells per microscopic field for MMP-9 and for MMP-2 in type I, II, and III achalasia patients and esophageal tissue of transplant donors. b Overall tissue expression of MMP-9 and MMP-2 in an achalasia cohort. The results are expressed as mean (horizontal dotted line), median (solid line), and 5th/95th percentiles of MMP-9⁺ and MMP-2⁺ cells. Transplant donors (TD) were included as controls. *p < 0.05. Numbers of analyzed biopsies are provided together with the color codes