FIGURE 1.

Overview of early kidney development in mouse. At embryonic day 11.0, the ureteric bud (UB) grows out from the nephric duct (ND) and enters the metanephric mesenchyme (MM). By E11.5, the UB bifurcates into two distinct UB tips (T). The cloaca is indicated as (C), and the common nephric duct is indicated as (CND).