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. 2018 Nov 12;9:952. doi: 10.3389/fneur.2018.00952

Table 2.

Odds ratios for TC, LDL-C and HDL-C among participants with dementia vs. normal, and with mild cognitive impairment vs. normal, by non-matched and PS matched models.

Non-matched Models PS Matched Models
MCI vs. Normal Dementia vs. Normal MCI vs. Normal Dementia vs. Normal
n OR (95%CI) P for trend n OR (95%CI) P for trend n OR (95%CI) P for trend n OR (95%CI) P for trend
TC 0.6118 0.2349 0.7690 0.1290
    Low 1,063 1.00 (reference) 899 1.00 (reference) 720 1.00 (reference) 612 1.00 (reference)
    Moderate 1,085 1.00 (0.79, 1.26) 919 0.76 (0.42, 1.35) 730 1.06 (0.80, 1.41) 610 0.76 (0.38, 1.54)
    High 1,076 0.95 (0.74, 1.21) 923 0.69 (0.37, 1.27) 728 0.96 (0.73, 1.28) 615 0.56 (0.27, 1.19)
LDL-C 0.3684 0.5047 0.9439 0.0405*
    Low 991 1.00 (reference) 845 1.00 (reference) 815 1.00 (reference) 704 1.00 (reference)
    Moderate 1,215 1.02 (0.81, 1.28) 1,026 0.67 (0.39, 1.18) 825 1.00 (0.77, 1.31) 699 0.61 (0.32, 1.15)
    High 1,018 0.99 (0.77, 1.26) 870 0.56 (0.30, 1.04) 830 0.99 (0.76, 1.30) 706 0.50 (0.26, 0.98)
HDL-C 0.2196 0.0084** 0.7776 0.5566
    Low 1,070 1.00 (reference) 909 1.00 (reference) 666 1.00 (reference) 575 1.00 (reference)
    Moderate 1,106 1.06 (0.84, 1.34) 938 0.89 (0.47, 1.66) 678 1.14 (0.84, 1.53) 574 0.81 (0.36, 1.82)
    High 1,048 1.06 (0.82, 1.36) 894 1.18 (0.64, 2.18) 661 1.05 (0.78, 1.43) 572 1.21 (0.59, 2.47)

Non-matched models and PS matched models adjusted for age, sex, years of education, ApoE-ε4 allele carrier status, BMI, depression, diabetes mellitus, hypertension and stroke.

*

P-value < 0.05, **P-value < 0.01.

TC: low, < 4.87 mmol/L; moderate, 4.87–5.72 mmol/L; high, >5.72 mmol/L.

LDL-C: low, < 2.9 mmol/L; moderate, 2.9–3.7 mmol/L; high, >3.7 mmol/L.

HDL-C: low, < 1.17 mmol/L; moderate, 1.17–1.45 mmol/L; high, >1.45 mmol/L.