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Sections of control rats show normal architecture in the different parts of brain. Sections from the CdCl2-intoxicated group show extensive neuronal damage, apoptotic neurones, and degeneration of Purkinje neurones. Sections of the SME-treated group show a normal structure. Sections of brains where SME was pre-administered to CdCl2 show improvement in the neuronal structure (H&E, ×400).
