Figure 1.

Sln deletion as depicted by western blotting (A) does not alter maximal SERCA activity (B) but does enhance SERCA’s apparent affinity for Ca²⁺ in soleus and diaphragm muscles (C–E) from mdx mice. Western blot analyses of SERCA1a (F) and SERCA2a (G) did not reveal any significant differences. For (C), ^*denotes a significant main effect when using a two-way ANOVA, P ≤ 0.05, n = 5−6 per group.