Table 3.
Rates, unadjusted, and adjusted hazard ratios from Cox regression for attrition among participants who ever started SMCC
| All patients (N = 18,363) | Attritions | Person‐years (py) | Attrition rate/1000 py | Unadjusted Cox model | Adjusted Cox modela | ||
|---|---|---|---|---|---|---|---|
| cHR (95% CI) | p‐value | aHR (95% CI) | p‐value | ||||
| SMCC periods | |||||||
| Eligible and off SMCC | 188 | 3584 | 52.5 | 2.3 (2.0 to 2.8) | <0.01 | 2.6 (2.2 to 3.1) | <0.01 |
| Eligible and on SMCC | 751 | 28,466 | 26.4 | 1.0 | 1.0 | ||
| Not eligible and off SMCC | 87 | 1713 | 50.8 | 2.3 (1.8 to 2.9) | <0.01 | 2.4 (1.9 to 3.0) | <0.01 |
| Not eligible and on SMCC | 25 | 903 | 27.7 | 1.1 (0.7 to 1.6) | 0.7 | 1.2 (0.8 to 1.8) | 0.36 |
| Sex | |||||||
| Male | 404 | 11,750 | 37.9 | 1.2 (1.1 to 1.4) | <0.01 | 1.3 (1.2 to 1.5) | <0.01 |
| Female | 647 | 22,916 | 30.5 | 1.0 | 1.0 | ||
| Age at baseline | |||||||
| 18 to 24 | 54 | 778 | 53.1 | 2.6 (2.0 to 3.5) | <0.01 | 2.6 (1.9 to 3.4) | <0.01 |
| 25 to 34 | 347 | 10,102 | 34.4 | 1.3 (1.1 to 1.5) | <0.01 | 1.3 (1.1 to 1.5) | <0.01 |
| 35 to 44 | 368 | 13,899 | 26.5 | 1.0 | 1.0 | ||
| ≥45 | 282 | 25,380 | 28.5 | 1.1 (0.9 to 1.3) | 0.41 | 1.1 (0.9 to 1.2) | 0.44 |
| Size of health centre | |||||||
| District hospital | 152 | 4500 | 33.8 | 1.0 (0.9 to 1.2) | 0.91 | 1.0 (0.9 to 1.3) | 0.5 |
| Large health centre | 292 | 11,547 | 25.3 | 0.8 (0.7 to 0.9) | <0.01 | 0.8 (0.7 to 0.9) | <0.01 |
| Medium health centre | 601 | 18213 | 33.0 | 1.0 | 1.0 | ||
| Other | 6 | 405 | 14.8 | 0.5 (0.2 to 1.0) | 0.05 | 0.6 (0.2 to 1.2) | 0.15 |
| Year of first SMCC eligibility | |||||||
| 2008 to 2009 | 353 | 15,796 | 22.3 | 1.0 | 1.0 | ||
| 2010 to 2011 | 310 | 9535 | 32.5 | 1.5 (1.3 to 1.8) | <0.01 | 1.7 (1.4 to 2.0) | <0.01 |
| 2012 to 2013 | 300 | 7298 | 41.1 | 2.1 (1.7 to 2.4) | <0.01 | 2.4 (2.0 to 2.9) | <0.01 |
| 2014 to 2015 | 89 | 2037 | 43.7 | 2.2 (1.7 to 2.8) | <0.01 | 2.3 (1.8 to 3.1) | <0.01 |
| Last pre‐SMCC CD4 b | |||||||
| <300 | 36 | 984 | 50.7 | 1.2 (0.8 to 1.6) | 0.41 | 0.9 (0.7 to 1.4) | 0.78 |
| 300 to 499 | 420 | 13,807 | 33.5 | 1.0 | |||
| ≥500 | 523 | 18,544 | 30.7 | 0.9 (0.8 to 1.1) | 0.24 | 1.0 (0.9 to 1.2) | 0.89 |
| Missing | 72 | 133 | 68.2 | 1.7 (1.3 to 2.2) | <0.01 | 1.7 (1.3 to 2.2) | <0.01 |
| Month since ART start | |||||||
| <24 months | 386 | 12,337 | 31.3 | 1.2 (1.0 to 1.4) | 0.05 | 0.9 (0.7 to 1.2) | 0.33 |
| 24 to 47 months | 457 | 15,799 | 28.9 | 1.1 (1.0 to 1.3) | 0.20 | 1.1 (0.9 to 1.4) | 0.5 |
| ≥48 months | 316 | 11974 | 26.4 | 1.0 | 1.0 | ||
| Month since first visit | |||||||
| <24 months | 261 | 7685 | 34.0 | 1.2 (1.1 to 1.4) | 0.04 | 1.1 (0.8 to 1.4) | 0.49 |
| 24 to 47 months | 429 | 16,011 | 26.8 | 1.0 (0.8 to 1.1) | 0.64 | 0.8 (0.7 to 1.0) | 0.05 |
| ≥48 months | 469 | 16,413 | 28.6 | 1.0 | 1.0 | ||
| Cumulative WHO Stage 3/4b | |||||||
| Recorded | 572 | 18,140 | 31.6 | 1.1 (1.0 to 1.2) | 0.17 | 1.2 (1.0 to 1.3) | 0.02 |
| Not recorded | 479 | 16,526 | 29.0 | 1.0 | 1.0 | ||
SMCC, six‐monthly clinical consultations; ART, antiretroviral therapy, cHR, crude hazard ratio; aHR, adjusted hazard ratio.
aAdjusted for all variables in the table; bpast year.