Table 4.

Area under curve in ten separate trials of randomly splitting training (75%) and trail data (25%) and the resulting accuracy of prediction in the trial set

Trial	ROC analysis	95% CI	Sens (%)	Spec (%)	P value	Accuracy  (%) in trial set
	AUC
1	0.925	0.871–0.961	86.5	87.5	<.0001	68
2	0.896	0.837–0.940	78.4	90.0	<.0001	84
3	0.899	0.840–0.942	85.1	85.0	<.0001	82
4	0.921	0.867–0.958	94.6	78.8	<.0001	78
5	0.910	0.854–0.950	89.2	85.0	<.0001	76
6	0.906	0.849–0.947	89.2	81.3	<.0001	84
7	0.917	0.861–0.955	86.5	87.5	<.0001	70
8	0.930	0.878–0.965	89.2	87.5	<.0001	66
9	0.904	0.846–0.946	89.2	80.0	<.0001	82
10	0.906	0.849–0.947	85.1	85.0	<.0001	72

Abbreviations: ROC, receiver operating characteristic; AUC, area under curve, CI, confidence interval; Sens, sensitivity; Spec, specificity.